PDB entry 3rn2

View 3rn2 on RCSB PDB site
Description: Structural Basis of Cytosolic DNA Recognition by Innate Immune Receptors
Class: Immune system/DNA
Keywords: CYTOSOLIC DNA SENSOR, INFLAMMASOME, DNA BINDING, CYTOSOLIC, Immune system-DNA complex
Deposited on 2011-04-21, released 2012-04-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-09, with a file datestamp of 2012-05-04.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.21
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interferon-inducible protein AIM2
    Species: Homo sapiens [TaxId:9606]
    Gene: AIM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3rn2a1, d3rn2a2
  • Chain 'B':
    Compound: Interferon-inducible protein AIM2
    Species: Homo sapiens [TaxId:9606]
    Gene: AIM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3rn2b1, d3rn2b2
  • Chain 'K':
    Compound: DNA (5'-d(*cp*cp*ap*tp*cp*ap*ap*ap*gp*ap*tp*cp*tp*tp*tp*gp*ap*tp*gp*g)-3')
  • Chain 'L':
    Compound: DNA (5'-d(*cp*cp*ap*tp*cp*ap*ap*ap*gp*ap*tp*cp*tp*tp*tp*gp*ap*tp*gp*g)-3')
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rn2A (A:)
gsvdsiregfqkrclpvmvlkakkpftfetqegkqemfhatvatekefffvkvfntllkd
kfipkriiiiaryyrhsgflevnsasrvldaesdqkvnvplniirkagetpkintlqtqp
lgtivnglfvvqkvtekkknilfdlsdntgkmevlgvrnedtmkckegdkvrltfftlsk
ngeklqltsgvhstikvikakkktaaas

    Sequence, based on observed residues (ATOM records): (download) 
    >3rn2A (A:)
egfqkrclpvmvlkakkpftfetqegkqemfhatvatekefffvkvfntllkdkfipkri
iiiaryyrhsgflevnsasrvldaesdqkvnvplniirkagetpkintlqtqplgtivng
lfvvqkvtekkknilfdlsdntgkmevlgvrnedtmkckegdkvrltfftlskngeklql
tsgvhstikvikak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3rn2B (B:)
gsvdsiregfqkrclpvmvlkakkpftfetqegkqemfhatvatekefffvkvfntllkd
kfipkriiiiaryyrhsgflevnsasrvldaesdqkvnvplniirkagetpkintlqtqp
lgtivnglfvvqkvtekkknilfdlsdntgkmevlgvrnedtmkckegdkvrltfftlsk
ngeklqltsgvhstikvikakkktaaas

    Sequence, based on observed residues (ATOM records): (download) 
    >3rn2B (B:)
egfqkrclpvmvlkakkpftfetqegkqemfhatvatekefffvkvfntllkdkfipkri
iiiaryyrhsgflevnsasrvldaesdqkvnvplniirkagetpkintlqtqplgtivng
lfvvqkvtekkknilfdlsdntgkmevlgvrnedtmkckegdkvrltfftlskngeklql
tsgvhstikvika

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.