PDB entry 3rll

View 3rll on RCSB PDB site
Description: Crystal structure of the T877A androgen receptor ligand binding domain in complex with (S)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanonaphthalen-1-yloxy)-2-hydroxy-2-methylpropanamide
Class: transcription
Keywords: steroid receptor, DHT, TESTOSTERONE, TRANSCRIPTION
Deposited on 2011-04-19, released 2011-05-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-06-15, with a file datestamp of 2011-06-10.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.235
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AR, DHTR, NR3C4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10275 (Start-246)
      • engineered mutation (206)
    Domains in SCOPe 2.01: d3rlla_
  • Heterogens: RLL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rllA (A:)
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
scsrrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgk
vkpiyfh

    Sequence, based on observed residues (ATOM records): (download) 
    >3rllA (A:)
iflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhvd
dqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhls
qefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiacsrrfyql
tklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyfh