PDB entry 3rjf

View 3rjf on RCSB PDB site
Description: Ternary complex of DNA Polymerase Beta with a gapped DNA containing (syn)8odG at template position paired with non-hydrolyzable dATP analog (dApCPP)
Class: Transferase, Lyase/DNA
Keywords: Mutagenesis, G-T Transversion, DNA Polymerase, oxidative Damage, Transferase, Lyase-DNA complex
Deposited on 2011-04-15, released 2012-01-18
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-01-18, with a file datestamp of 2012-01-13.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.193
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3rjfa1, d3rjfa2, d3rjfa3
  • Chain 'D':
    Compound: DNA (5'-d(p*gp*tp*cp*gp*g)-3')
  • Chain 'P':
    Compound: DNA (5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*a)-3')
  • Chain 'T':
    Compound: DNA (5'-d(*cp*cp*gp*ap*cp*(8og)p*tp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3')
  • Heterogens: F2A, MG, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rjfA (A:)
mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
lgvtgvageplpvdsekdifdyiqwkyrepkdrse

    Sequence, based on observed residues (ATOM records): (download) 
    >3rjfA (A:)
tlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtki
aekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkne
dklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessg
dmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndeke
yphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvage
plpvdsekdifdyiqwkyrepkdrse

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.