PDB entry 3r7i

View 3r7i on RCSB PDB site
Description: CDK2 in complex with inhibitor KVR-1-74
Class: transferase/transferase inhibitor
Keywords: protein kinase, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-03-22, released 2012-08-08
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-08-08, with a file datestamp of 2012-08-03.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.195
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3r7ia_
  • Heterogens: EDO, X9I, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3r7iA (A:)
gplgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstairei
sllkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqll
qglafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrape
illgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvts
mpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkp
vphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >3r7iA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirpstaireisllkelnhpnivklld
vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
kpqnllintegaikladfglarafgvvvtlwyrapeillgckyystavdiwslgcifaem
vtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppld
edgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl