SCOPe 2.08: Structural Classification of Proteins

PDB entry 3r2b

View 3r2b on RCSB PDB site
Description: MK2 kinase bound to Compound 5b
Class: transferase/transferase inhibitor
Keywords: Kinase domain with bound inhibitor, Kinase domain, Phosphotransferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-03-14, released 2011-05-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-07-08.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.279
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2ba_
Chain 'B':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bb_
Chain 'C':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bc_
Chain 'D':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bd_
Chain 'E':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2be_
Chain 'F':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bf_
Chain 'G':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bg_
Chain 'H':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bh_
Chain 'I':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bi_
Chain 'J':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bj_
Chain 'K':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bk_
Chain 'L':
Compound: MAP kinase-activated protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MAPKAPK2
Database cross-references and differences (RAF-indexed):
- Uniprot P49137 (0-End)
Domains in SCOPe 2.08: d3r2bl_
Heterogens: 05B

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3r2bA (A:)
hvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarreve
lhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqaftereasei
mksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnslttpcyt
pyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqyef
pnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedk
erwedvkeemtsalatmr