PDB entry 3qzw

View 3qzw on RCSB PDB site
Description: Plasticity of human CD8 binding to peptide-HLA-A*2402
Class: immune system
Keywords: Immunoglobulin family, IMMUNE SYSTEM, coreceptor
Deposited on 2011-03-07, released 2011-06-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.205
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-24 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.06: d3qzwb1, d3qzwb2
  • Chain 'C':
    Compound: 10-mer peptide from Protein Nef
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: HLA class I histocompatibility antigen, A-24 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.06: d3qzwe1, d3qzwe2
  • Chain 'F':
    Compound: 10-mer peptide from Protein Nef
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: T-cell surface glycoprotein CD8 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CD8A, MAL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qzwg_
  • Chain 'H':
    Compound: T-cell surface glycoprotein CD8 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CD8A, MAL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qzwh_
  • Chain 'I':
    Compound: T-cell surface glycoprotein CD8 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CD8A, MAL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qzwi_
  • Chain 'J':
    Compound: T-cell surface glycoprotein CD8 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CD8A, MAL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qzwj_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qzwB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qzwE (E:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qzwG (G:)
    sqfrvspldrtwnlgetvelkcqvllsnptsgcswlfqprgaaasptfllylsqnkpkaa
    egldtqrfsgkrlgdtfvltlsdfrrenegyyfcsalsnsimyfshfvpvflpa
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qzwH (H:)
    sqfrvspldrtwnlgetvelkcqvllsnptsgcswlfqprgaaasptfllylsqnkpkaa
    egldtqrfsgkrlgdtfvltlsdfrrenegyyfcsalsnsimyfshfvpvflpa
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qzwI (I:)
    sqfrvspldrtwnlgetvelkcqvllsnptsgcswlfqprgaaasptfllylsqnkpkaa
    egldtqrfsgkrlgdtfvltlsdfrrenegyyfcsalsnsimyfshfvpvflpa
    

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3qzwJ (J:)
    sqfrvspldrtwnlgetvelkcqvllsnptsgcswlfqprgaaasptfllylsqnkpkaa
    egldtqrfsgkrlgdtfvltlsdfrrenegyyfcsalsnsimyfshfvpvflpa