PDB entry 3qxw

View 3qxw on RCSB PDB site
Description: Free structure of an anti-methotrexate CDR1-4 Graft VHH Antibody
Class: immune system
Keywords: Camelid Single Domain Antibody, Heavy Chain Only, VHH, Antibody, Anti-Hapten Antibody, CDR, Hapten Binding, Small Molecule Sensing, Ligand Binding, Low Molecular Weight Compound, Methotrexate, IMMUNE SYSTEM
Deposited on 2011-03-02, released 2011-07-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Anti-Methotrexate CDR1-4 Graft VHH
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QXW (Start-125)
    Domains in SCOPe 2.08: d3qxwa_
  • Chain 'B':
    Compound: Anti-Methotrexate CDR1-4 Graft VHH
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QXW (Start-125)
    Domains in SCOPe 2.08: d3qxwb_
  • Chain 'C':
    Compound: Anti-Methotrexate CDR1-4 Graft VHH
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QXW (Start-125)
    Domains in SCOPe 2.08: d3qxwc_
  • Chain 'D':
    Compound: Anti-Methotrexate CDR1-4 Graft VHH
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QXW (Start-125)
    Domains in SCOPe 2.08: d3qxwd_
  • Chain 'E':
    Compound: Anti-Methotrexate CDR1-4 Graft VHH
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 3QXW (Start-125)
    Domains in SCOPe 2.08: d3qxwe_
  • Heterogens: NA, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qxwA (A:)
gsqvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrlt
tygdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgt
qvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >3qxwA (A:)
qvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrltty
gdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgtqv
tvss

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qxwB (B:)
gsqvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrlt
tygdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgt
qvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >3qxwB (B:)
qvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrltty
gdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgtqv
tvss

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qxwC (C:)
gsqvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrlt
tygdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgt
qvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >3qxwC (C:)
vqlvesggglvqaggslrlscaasrswamawfrqapgkerefvakisgdgrlttygdsvk
grftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgtqvtvss

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qxwD (D:)
gsqvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrlt
tygdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgt
qvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >3qxwD (D:)
vqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrlttyg
dsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgtqvt
vss

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3qxwE (E:)
gsqvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrlt
tygdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgt
qvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >3qxwE (E:)
qvqlvesggglvqaggslrlscaasrrssrswamawfrqapgkerefvakisgdgrltty
gdsvkgrftisrdnaeylvylqmdslkpedtavyycaaddnyvtaswrsgpdywgqgtqv
tvss