PDB entry 3qvu

View 3qvu on RCSB PDB site
Description: Crystal structure of Ancestral variant b9 of SULT 1A1 in complex with PAP and p-nitrophenol
Class: transferase
Keywords: transferase, aryl sulfotransferase
Deposited on 2011-02-26, released 2011-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-08-31, with a file datestamp of 2011-08-26.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.21
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sulfotransferase 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: SULT1A1, STP, STP1, OK/SW-cl.88
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50225 (Start-294)
      • engineered mutation (9)
      • engineered mutation (76)
      • engineered mutation (150)
      • engineered mutation (167)
      • variant (212)
      • variant (222)
      • engineered mutation (242)
      • engineered mutation (246)
    Domains in SCOPe 2.08: d3qvua_
  • Chain 'B':
    Compound: Sulfotransferase 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: SULT1A1, STP, STP1, OK/SW-cl.88
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50225 (Start-294)
      • engineered mutation (9)
      • engineered mutation (76)
      • engineered mutation (150)
      • engineered mutation (167)
      • variant (212)
      • variant (222)
      • engineered mutation (242)
      • engineered mutation (246)
    Domains in SCOPe 2.08: d3qvub_
  • Heterogens: NPO, EDO, A3P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qvuA (A:)
meliqdtsrqpleyvkgvplikyfaealgplqsfqarpddllistypksgttwvsqildm
iyqggdlekchrapifnrvpflefkapgipsgmetlkdtpaprllkthlplallpqtlld
qkvkvvyvarnakdvavsyyhfyhmakvhpdpgtwdsflekfmvgevcygswyqhvqeww
elsrthpvlylfyedmkenpkreiqkilefvghslpeetvdfmvqhtsfkemkknpmtny
ttipqeimdhsispfmrkgmagdwkttftvaqnerfdadyaekmagcslsfrsel

    Sequence, based on observed residues (ATOM records): (download) 
    >3qvuA (A:)
srqpleyvkgvplikyfaealgplqsfqarpddllistypksgttwvsqildmiyqggdl
ekchrapifnrvpflefkapgipsgmetlkdtpaprllkthlplallpqtlldqkvkvvy
varnakdvavsyyhfyhmakvhpdpgtwdsflekfmvgevcygswyqhvqewwelsrthp
vlylfyedmkenpkreiqkilefvghslpeetvdfmvqhtsfkemkknpmtnyttipqei
mdhsispfmrkgmagdwkttftvaqnerfdadyaekmagcslsfrsel

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qvuB (B:)
meliqdtsrqpleyvkgvplikyfaealgplqsfqarpddllistypksgttwvsqildm
iyqggdlekchrapifnrvpflefkapgipsgmetlkdtpaprllkthlplallpqtlld
qkvkvvyvarnakdvavsyyhfyhmakvhpdpgtwdsflekfmvgevcygswyqhvqeww
elsrthpvlylfyedmkenpkreiqkilefvghslpeetvdfmvqhtsfkemkknpmtny
ttipqeimdhsispfmrkgmagdwkttftvaqnerfdadyaekmagcslsfrsel

    Sequence, based on observed residues (ATOM records): (download) 
    >3qvuB (B:)
srqpleyvkgvplikyfaealgplqsfqarpddllistypksgttwvsqildmiyqggdl
ekchrapifnrvpflefkapgipsgmetlkdtpaprllkthlplallpqtlldqkvkvvy
varnakdvavsyyhfyhmakvhpdpgtwdsflekfmvgevcygswyqhvqewwelsrthp
vlylfyedmkenpkreiqkilefvghslpeetvdfmvqhtsfkemkknpmtnyttipqei
mdhsispfmrkgmagdwkttftvaqnerfdadyaekmagcslsfrsel