PDB entry 3qpy

View 3qpy on RCSB PDB site
Description: Crystal structure of a mutant (K57A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis
Class: transferase
Keywords: manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, biosynthesis, transferase, lyase, lipopolysaccharide biosynthesis
Deposited on 2011-02-14, released 2011-04-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-05, with a file datestamp of 2014-02-28.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.207
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (56)
    Domains in SCOPe 2.08: d3qpya_
  • Chain 'B':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (56)
    Domains in SCOPe 2.08: d3qpyb_
  • Chain 'C':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (56)
    Domains in SCOPe 2.08: d3qpyc_
  • Chain 'D':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (56)
    Domains in SCOPe 2.08: d3qpyd_
  • Heterogens: CL, NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qpyA (A:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpyA (A:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqgrraqaldlalagmatrlaglfleslhlledflirika
lddliksqpi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qpyB (B:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpyB (B:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqrraqaldlalagmatrlaglfleshlledflirikald
dliksqpilt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qpyC (C:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpyC (C:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslraqaldlalagmatrlaglflesalplhlledflirika
lddliksqpil

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qpyD (D:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpyD (D:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdaanr
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtraqaldlalagmatrlaglfleslhlledflirikal
ddliksqpi