PDB entry 3qow

View 3qow on RCSB PDB site
Description: DOT1L Structure in complex with SAM
Class: transferase
Keywords: H3K79 methylation, TRANSFERASE
Deposited on 2011-02-11, released 2011-05-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-08-10, with a file datestamp of 2011-08-05.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.162
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: DOT1L, KIAA1814, KMT4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qowa_
  • Heterogens: SAM, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qowA (A:)
mhhhhhhssgmgeklelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipd
lklamenyvlidydtksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhi
lqqvynhsvtdpeklnnyepfspevygetsfdlvaqmideikmtdddlfvdlgsgvgqvv
lqvaaatnckhhygvekadipakyaetmdrefrkwmkwygkkhaeytlergdflseewre
riantsvifvnnfafgpevdhqlkerfanmkeggrivsskpfaplnfrinsrnlsdigti
mrvvelsplkgsvswtgkpvsyylhtidrtilenyfsslknpklreeqeaarrrqqresk
snaatptkgpegkvagpadapmdsgaeeekagaatvkkpspskarkkklnkkgrkmagrk
rgrpkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3qowA (A:)
klelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenylidyd
tksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpek
lnnyepfspevygetsfdlvaqmideikmtdddlfvdlgsgvgqvvlqvaaatnckhhyg
vekadipakyaetmdrefrkwmkwygkkhaeytlergdflseewreriantsvifvnnfa
fgpevdhqlkerfanmkeggrivsskpfaplnfrinsrnlsdigtimrvvelsplkwtgk
pvsyylhtidrtilenyfsslk