PDB entry 3qj7

View 3qj7 on RCSB PDB site
Description: Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP
Class: transferase
Keywords: Thymidilate synthase, Structural Genomics, TB Structural Genomics Consortium, TBSGC, TRANSFERASE
Deposited on 2011-01-28, released 2011-06-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: MT2834, MTV002.29c, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qj7a_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: MT2834, MTV002.29c, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qj7b_
  • Chain 'C':
    Compound: Thymidylate synthase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: MT2834, MTV002.29c, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qj7c_
  • Chain 'D':
    Compound: Thymidylate synthase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: MT2834, MTV002.29c, thyA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67044 (1-263)
      • expression tag (0)
    Domains in SCOPe 2.08: d3qj7d1, d3qj7d2
  • Heterogens: UMP, SPM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qj7A (A:)
smtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayel
lwflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldll
rtdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnia
syallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsif
eytyedivvknydphpaikapvav

    Sequence, based on observed residues (ATOM records): (download) 
    >3qj7A (A:)
mtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayell
wflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllr
tdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnias
yallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsife
ytyedivvknydphpaikap

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qj7B (B:)
smtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayel
lwflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldll
rtdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnia
syallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsif
eytyedivvknydphpaikapvav

    Sequence, based on observed residues (ATOM records): (download) 
    >3qj7B (B:)
mtpyedllrfvletgtpksgtgtrslfgqqmrydlsagfpllttkkvhfksvayellwfl
rgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllrtdp
dsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfniasyal
lthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsifeyty
edivvknydphpaikap

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qj7C (C:)
smtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayel
lwflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldll
rtdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnia
syallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsif
eytyedivvknydphpaikapvav

    Sequence, based on observed residues (ATOM records): (download) 
    >3qj7C (C:)
mtpyedllrfvletgtpksdgtgtrslfgqqmrydlsagfpllttkkvhfksvayellwf
lrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllrtd
pdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfniasya
llthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsifeyt
yedivvknydphpaikapv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qj7D (D:)
smtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayel
lwflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldll
rtdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnia
syallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsif
eytyedivvknydphpaikapvav

    Sequence, based on observed residues (ATOM records): (download) 
    >3qj7D (D:)
smtpyedllrfvletgtpksgtgtrslfgqqmrydlsagfpllttkkvhfksvayellwf
lrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllrtd
pdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfniasya
llthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsifeyt
yedivvknydphpaikapvav