PDB entry 3qip

View 3qip on RCSB PDB site
Description: Structure of HIV-1 reverse transcriptase in complex with an RNase H inhibitor and nevirapine
Class: transferase/transferase inhibitor
Keywords: HIV, reverse transcriptase, RNase H, polymerase, nuclease, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-01-27, released 2011-04-20
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: 0.219
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse HIV-1 reverse transcriptase p66
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: p51
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3qipb_
  • Heterogens: NVP, MN, SO4, CL, P4Y, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3qipB (B:)
    pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
    faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
    dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
    yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
    vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
    lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
    htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
    plvklwyqlekepivgaetf
    

    Sequence, based on observed residues (ATOM records): (download)
    >3qipB (B:)
    etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
    stkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrky
    taftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddl
    yvgsdleigqhrtkieelrqhllrwgltyelhpdkwtvqpivlpekdswtvndiqklvgk
    lnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpsk
    dliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkittesiviwgktpk
    fklpiqketwetwwteywqatwipewefvntpplvklwyqle