PDB entry 3qft

View 3qft on RCSB PDB site
Description: Crystal Structure of NADPH-Cytochrome P450 Reductase (FAD/NADPH domain and R457H Mutant)
Class: oxidoreductase
Keywords: NADPH-Cytochrome P450 Reductase, flavoprotein, Antley-Bixler syndrome, FAD, NADPH, OXIDOREDUCTASE
Deposited on 2011-01-22, released 2011-08-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-08-31, with a file datestamp of 2011-08-26.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.205
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADPH--cytochrome P450 reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: POR, CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16435 (Start-457)
      • engineered mutation (234)
      • see remark 999 (280)
    Domains in SCOPe 2.05: d3qfta1, d3qfta2
  • Heterogens: FAD, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qftA (A:)
mgsshhhhhhssglvprgshmsirqyelvvhtdidaakvymgemgrlksyenqkppfdak
npflaavttnrklnqgterhlmhleldisdskiryesgdhvavypandsalvnqlgkilg
adldvvmslnnldeesnkkhpfpcptsyrtaltyylditnpprtnvlyelaqyasepseq
ellrkmasssgegkelylswvvearrhilailqdcpslrppidhlcellprlqahyysia
ssskvhpnsvhicavvveyetkagrinkgvatnwlrakepvgenggralvpmfvrksqfr
lpfkattpvimvgpgtgvapfigfiqerawlrqqgkevgetllyygcrrsdedylyreel
aqfhrdgaltqlnvafsreqshkvyvqhllkqdrehlwklieggahiyvcgdarnmardv
qntfydivaelgamehaqavdyikklmtkgrysldvws

    Sequence, based on observed residues (ATOM records): (download) 
    >3qftA (A:)
rqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterhlmh
leldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkhpfp
cptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylswvve
arrhilailqdcpslrppidhlcellprlqahyysiassskvhpnsvhicavvveyetka
grinkgvatnwlrakepvnggralvpmfvrksqfrlpfkattpvimvgpgtgvapfigfi
qerawlrqqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreqshkvy
vqhllkqdrehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqavdyikk
lmtkgrysldvws