PDB entry 3qe2

View 3qe2 on RCSB PDB site
Description: Crystal Structure of Human NADPH-Cytochrome P450 Reductase
Class: oxidoreductase
Keywords: CYPOR, cytochrome P450 reductase, Antley-Bixler Syndrome, flavoprotein, FMN, FAD, NADPH, OXIDOREDUCTASE
Deposited on 2011-01-19, released 2011-08-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-08-31, with a file datestamp of 2011-08-26.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.211
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADPH--cytochrome P450 reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: POR, CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16435 (Start-617)
      • see remark 999 (165)
      • see remark 999 (440)
    Domains in SCOPe 2.05: d3qe2a1, d3qe2a2, d3qe2a3
  • Chain 'B':
    Compound: NADPH--cytochrome P450 reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: POR, CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16435 (Start-617)
      • see remark 999 (165)
      • see remark 999 (440)
    Domains in SCOPe 2.05: d3qe2b1, d3qe2b2, d3qe2b3
  • Heterogens: FAD, FMN, NAP, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qe2A (A:)
gshmvressfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydl
adlsslpeidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktye
hfnamgkyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatgee
ssirqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterh
lmhleldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkh
pfpcptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylsw
vvearrhilailqdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveye
tkagrinkgvatnwlrakepvgenggralvpmfvrksqfrlpfkattpvimvgpgtgvap
figfiqerawlrqqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreq
shkvyvqhllkqdrehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqav
dyikklmtkgrysldvws

    Sequence, based on observed residues (ATOM records): (download) 
    >3qe2A (A:)
essfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladlssl
peidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktyehfnamg
kyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatssirqyelv
vhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterhlmhleldis
dskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkhpfpcptsyr
taltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylswvvearrhil
ailqdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveyetkagrinkg
vatnwlrakepvralvpmfvrksqfrlpfkattpvimvgpgtgvapfigfiqerawlrqq
gkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreqshkvyvqhllkqdr
ehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqavdyikklmtkgrysl
dvws

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qe2B (B:)
gshmvressfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydl
adlsslpeidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktye
hfnamgkyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatgee
ssirqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterh
lmhleldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkh
pfpcptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylsw
vvearrhilailqdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveye
tkagrinkgvatnwlrakepvgenggralvpmfvrksqfrlpfkattpvimvgpgtgvap
figfiqerawlrqqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreq
shkvyvqhllkqdrehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqav
dyikklmtkgrysldvws

    Sequence, based on observed residues (ATOM records): (download) 
    >3qe2B (B:)
essfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladlssl
peidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktyehfnamg
kyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatrqyelvvht
didaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterhlmhleldisdsk
iryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkhpfpcptsyrtal
tyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylswvvearrhilail
qdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveyetkagrinkgvat
nwlrakepvgenggralvpmfvrksqfrlpfkattpvimvgpgtgvapfigfiqerawlr
qqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreqshkvyvqhllkq
drehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqavdyikklmtkgry
sldvws