PDB entry 3qe2

View 3qe2 on RCSB PDB site
Description: Crystal Structure of Human NADPH-Cytochrome P450 Reductase
Class: oxidoreductase
Keywords: CYPOR, cytochrome P450 reductase, Antley-Bixler Syndrome, flavoprotein, FMN, FAD, NADPH, OXIDOREDUCTASE
Deposited on 2011-01-19, released 2011-08-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-08-31, with a file datestamp of 2011-08-26.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.211
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADPH--cytochrome P450 reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: POR, CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16435 (Start-617)
      • see remark 999 (165)
      • see remark 999 (440)
    Domains in SCOPe 2.04: d3qe2a1, d3qe2a2, d3qe2a3
  • Chain 'B':
    Compound: NADPH--cytochrome P450 reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: POR, CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16435 (Start-617)
      • see remark 999 (165)
      • see remark 999 (440)
    Domains in SCOPe 2.04: d3qe2b1, d3qe2b2, d3qe2b3
  • Heterogens: FAD, FMN, NAP, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3qe2A (A:)
    gshmvressfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydl
    adlsslpeidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktye
    hfnamgkyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatgee
    ssirqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterh
    lmhleldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkh
    pfpcptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylsw
    vvearrhilailqdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveye
    tkagrinkgvatnwlrakepvgenggralvpmfvrksqfrlpfkattpvimvgpgtgvap
    figfiqerawlrqqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreq
    shkvyvqhllkqdrehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqav
    dyikklmtkgrysldvws
    

    Sequence, based on observed residues (ATOM records): (download)
    >3qe2A (A:)
    essfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladlssl
    peidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktyehfnamg
    kyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatssirqyelv
    vhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterhlmhleldis
    dskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkhpfpcptsyr
    taltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylswvvearrhil
    ailqdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveyetkagrinkg
    vatnwlrakepvralvpmfvrksqfrlpfkattpvimvgpgtgvapfigfiqerawlrqq
    gkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreqshkvyvqhllkqdr
    ehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqavdyikklmtkgrysl
    dvws
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3qe2B (B:)
    gshmvressfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydl
    adlsslpeidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktye
    hfnamgkyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatgee
    ssirqyelvvhtdidaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterh
    lmhleldisdskiryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkh
    pfpcptsyrtaltyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylsw
    vvearrhilailqdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveye
    tkagrinkgvatnwlrakepvgenggralvpmfvrksqfrlpfkattpvimvgpgtgvap
    figfiqerawlrqqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreq
    shkvyvqhllkqdrehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqav
    dyikklmtkgrysldvws
    

    Sequence, based on observed residues (ATOM records): (download)
    >3qe2B (B:)
    essfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladlssl
    peidnalvvfcmatygegdptdnaqdfydwlqetdvdlsgvkfavfglgnktyehfnamg
    kyvdkrleqlgaqrifelglgdddgnleedfitwreqfwlavcehfgveatrqyelvvht
    didaakvymgemgrlksyenqkppfdaknpflaavttnrklnqgterhlmhleldisdsk
    iryesgdhvavypandsalvnqlgkilgadldvvmslnnldeesnkkhpfpcptsyrtal
    tyylditnpprtnvlyelaqyasepseqellrkmasssgegkelylswvvearrhilail
    qdcpslrppidhlcellprlqaryysiassskvhpnsvhicavvveyetkagrinkgvat
    nwlrakepvgenggralvpmfvrksqfrlpfkattpvimvgpgtgvapfigfiqerawlr
    qqgkevgetllyygcrrsdedylyreelaqfhrdgaltqlnvafsreqshkvyvqhllkq
    drehlwklieggahiyvcgdarnmardvqntfydivaelgamehaqavdyikklmtkgry
    sldvws