PDB entry 3qal

View 3qal on RCSB PDB site
Description: Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase
Class: transferase/transferase inhibitor
Keywords: Protein Kinase; Crystal Structure; Glu208/Arg280 Pair; Catalytic Subunit; PKA, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-01-11, released 2011-12-07
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-12-07, with a file datestamp of 2011-12-02.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.176
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Mus musculus [TaxId:10090]
    Gene: Prkaca, Pkaca
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05132 (0-349)
      • engineered mutation (279)
    Domains in SCOPe 2.01: d3qale_
  • Chain 'I':
    Compound: protein kinase inhibitor
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ATP, MG, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3qalE (E:)
gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
qvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffa
dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkafgnlkngvndiknhkwfatt
dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

    Sequence, based on observed residues (ATOM records): (download) 
    >3qalE (E:)
gnaasvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhy
amkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemf
shlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfak
rvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyek
ivsgkvrfpshfssdlkdllrnllqvdltkafgnlkngvndiknhkwfattdwiaiyqrk
veapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

  • Chain 'I':
    No sequence available.