PDB entry 3q0q

View 3q0q on RCSB PDB site
Description: Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREa
Class: RNA binding protein/RNA
Keywords: PUF, PUMILIO-homolgy domain, Gene regulation, RNA binding, RNA binding protein-RNA complex
Deposited on 2010-12-15, released 2011-03-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-06-19, with a file datestamp of 2013-06-14.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.197
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pumilio homolog 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PUM2, KIAA0235, PUMH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3q0qa_
  • Chain 'B':
    Compound: 5'-r(up*gp*up*ap*ap*ap*up*a)-3'
    Species: synthetic, synthetic
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3q0qA (A:)
    grsrlledfrnnrfpnlqlrdlighivefsqdqhgsrfiqqkleratpaerqmvfneilq
    aayqlmtdvfgnyviqkffefgsldqklalatrirghvlplalqmygcrviqkalesiss
    dqqvisemvkeldghvlkcvkdqngnhvvqkciecvqpqslqfiidafkgqvfvlsthpy
    gcrviqrilehctaeqtlpileelhqhteqlvqdqygnyviqhvlehgrpedkskivsei
    rgkvlalsqhkfasnvvekcvthasraerallidevccqndgphsalytmmkdqyanyvv
    qkmidmaepaqrkiimhkirphittlrkytygkhilaklekyylknspdlg
    

    Sequence, based on observed residues (ATOM records): (download)
    >3q0qA (A:)
    grsrlledfrnnrfpnlqlrdlighivefsqdqhgsrfiqqkleratpaerqmvfneilq
    aayqlmtdvfgnyviqkffefgsldqklalatrirghvlplalqmygcrviqkalesiss
    dqqvisemvkeldghvlkcvkdqngnhvvqkciecvqpqslqfiidafkgqvfvlsthpy
    gcrviqrilehctaeqtlpileelhqhteqlvqdqygnyviqhvlehgrpedkskivsei
    rgkvlalsqhkfasnvvekcvthasraerallidevccqndgphsalytmmkdqyanyvv
    qkmidmaepaqrkiimhkirphittlrkytygkhilaklekyy
    

  • Chain 'B':
    No sequence available.