PDB entry 3q0o

View 3q0o on RCSB PDB site
Description: Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE
Class: RNA binding protein/RNA
Keywords: PUF, PUMILIO-homolgy domain, Gene regulation, RNA binding, RNA binding protein-RNA complex
Deposited on 2010-12-15, released 2011-03-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-06-19, with a file datestamp of 2013-06-14.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.228
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pumilio homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PUM1, KIAA0099, PUMH1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3q0oa_
  • Chain 'B':
    Compound: Pumilio homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PUM1, KIAA0099, PUMH1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3q0ob_
  • Chain 'C':
    Compound: 5'-r(up*gp*up*ap*cp*ap*up*c)-3'
    Species: synthetic, synthetic
  • Chain 'D':
    Compound: 5'-r(up*gp*up*ap*cp*ap*up*c)-3'
    Species: synthetic, synthetic
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3q0oA (A:)
grsrlledfrnnrypnlqlreiaghimefsqdqhgsrfiqlkleratpaerqlvfneilq
aayqlmvdvfgnyviqkffefgsleqklalaerirghvlslalqmygcrviqkalefips
dqqnemvreldghvlkcvkdqngnhvvqkciecvqpqslqfiidafkgqvfalsthpygc
rviqrilehclpdqtlpileelhqhteqlvqdqygnyviqhvlehgrpedkskivaeirg
nvlvlsqhkfasnvvekcvthasrteravlidevctmndgphsalytmmkdqyanyvvqk
midvaepgqrkivmhkirphiatlrkytygkhilaklekyymkngvdlg

    Sequence, based on observed residues (ATOM records): (download) 
    >3q0oA (A:)
grsrlledfrnnrypnlqlreiaghimefsqdqhgsrfiqlkleratpaerqlvfneilq
aayqlmvdvfgnyviqkffefgsleqklalaerirghvlslalqmygcrviqkalefips
dqqnemvreldghvlkcvkdqngnhvvqkciecvqpqslqfiidafkgqvfalsthpygc
rviqrilehclpdqtlpileelhqhteqlvqdqygnyviqhvlehgrpedkskivaeirg
nvlvlsqhkfasnvvekcvthasrteravlidevctmndgphsalytmmkdqyanyvvqk
midvaepgqrkivmhkirphiatlrkytygkhilaklekyy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3q0oB (B:)
grsrlledfrnnrypnlqlreiaghimefsqdqhgsrfiqlkleratpaerqlvfneilq
aayqlmvdvfgnyviqkffefgsleqklalaerirghvlslalqmygcrviqkalefips
dqqnemvreldghvlkcvkdqngnhvvqkciecvqpqslqfiidafkgqvfalsthpygc
rviqrilehclpdqtlpileelhqhteqlvqdqygnyviqhvlehgrpedkskivaeirg
nvlvlsqhkfasnvvekcvthasrteravlidevctmndgphsalytmmkdqyanyvvqk
midvaepgqrkivmhkirphiatlrkytygkhilaklekyymkngvdlg

    Sequence, based on observed residues (ATOM records): (download) 
    >3q0oB (B:)
grsrlledfrnnrypnlqlreiaghimefsqdqhgsrfiqlkleratpaerqlvfneilq
aayqlmvdvfgnyviqkffefgsleqklalaerirghvlslalqmygcrviqkalefips
dqqnemvreldghvlkcvkdqngnhvvqkciecvqpqslqfiidafkgqvfalsthpygc
rviqrilehclpdqtlpileelhqhteqlvqdqygnyviqhvlehgrpedkskivaeirg
nvlvlsqhkfasnvvekcvthasrteravlidevctsalytmmkdqyanyvvqkmidvae
pgqrkivmhkirphiatlrkytygkhilaklekyy

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.