PDB entry 3pxq

View 3pxq on RCSB PDB site
Description: CDK2 in complex with 3 molecules of 8-anilino-1-naphthalene sulfonate
Class: transferase
Keywords: protein kinase, CDK2, allosteric ligand, ANS, TRANSFERASE
Deposited on 2010-12-10, released 2011-02-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.196
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (8-305)
      • expression tag (4-7)
    Domains in SCOPe 2.03: d3pxqa_
  • Heterogens: EDO, 2AN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pxqA (A:)
gplgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstairei
sllkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqll
qglafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrape
illgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvts
mpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkp
vphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >3pxqA (A:)
spefmenfqkvekigegtygvvykarnkltgevvalkkirtegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl