PDB entry 3pp3
View 3pp3 on RCSB PDB site
Description: Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies
Class: immune system
Keywords: antibody Fab-fragment Ig-domain, antibody, CD20, IMMUNE SYSTEM
Deposited on
2010-11-24, released
2011-04-13
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-27, with a file datestamp of
2011-07-22.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: 0.21
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: GA101 Fab heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'I':
Compound: GA101 Fab heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'K':
Compound: GA101 Fab light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3pp3k1, d3pp3k2 - Chain 'L':
Compound: GA101 Fab light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3pp3l1, d3pp3l2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'H':
No sequence available.
- Chain 'I':
No sequence available.
- Chain 'K':
Sequence; same for both SEQRES and ATOM records: (download)
>3pp3K (K:)
divmtqtplslpvtpgepasiscrssksllhsngitylywylqkpgqspqlliyqmsnlv
sgvpdrfsgsgsgtdftlkisrveaedvgvyycaqnlelpytfgggtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>3pp3L (L:)
divmtqtplslpvtpgepasiscrssksllhsngitylywylqkpgqspqlliyqmsnlv
sgvpdrfsgsgsgtdftlkisrveaedvgvyycaqnlelpytfgggtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec