PDB entry 3pmn

View 3pmn on RCSB PDB site
Description: ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site
Class: lyase,transferase/DNA
Keywords: PROTEIN-DNA COMPLEX, LYASE, TRANSFERASE, DNA, LYASE,TRANSFERASE-DNA complex
Deposited on 2010-11-17, released 2011-02-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-02-16, with a file datestamp of 2011-02-11.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.213
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase lambda
    Species: Homo sapiens [TaxId:9606]
    Gene: POLL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGP5 (Start-328)
      • see remark 999 (221-222)
      • see remark 999 (223-224)
    Domains in SCOPe 2.06: d3pmna1, d3pmna2, d3pmna3
  • Chain 'B':
    Compound: 5'-d(*cp*gp*gp*cp*cp*tp*tp*ap*cp*tp*g)-3'
  • Chain 'C':
    Compound: 5'-d(*cp*ap*gp*tp*ap*g)-3'
  • Chain 'D':
    Compound: 5'-d(*gp*cp*cp*g)-3'
  • Heterogens: 1GC, MG, MN, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pmnA (A:)
aqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacs
ipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsle
dirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrg
katcgdvdvlithpdgrshrgifsrlldslrqegfltddlvkgetkylgvcrlpgpgrrh
rrldiivvpysefacallyftgsahfnrsmralaktkgmslsehalstavvrnthgckvg
pgrvlptptekdvfrllglpyrepaerdw

    Sequence, based on observed residues (ATOM records): (download) 
    >3pmnA (A:)
atnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipgigkr
maekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledirsqas
lttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdv
dvlithpdgrshrgifsrlldslrqegfltddlvkgetkylgvcrlpgpgrrhrrldiiv
vpysefacallyftgsahfnrsmralaktkgmslsehalstavpgrvlptptekdvfrll
glpyrepaerdw

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.