PDB entry 3pa5

View 3pa5 on RCSB PDB site
Description: X-ray crystal structure of compound 1 bound to human CHK1 kinase domain
Class: transferase/transferase inhibitor
Keywords: kinase, phosphatase, transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-10-18, released 2010-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-12-08, with a file datestamp of 2010-12-03.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.185
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase Chk1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHEK1, CHK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3pa5a_
  • Heterogens: C73, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pa5A (A:)
avpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkm
lnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvyl
hgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkr
refhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplal
lhkilvenpsaritipdikkdrwynkplkkgak

    Sequence, based on observed residues (ATOM records): (download) 
    >3pa5A (A:)
vpfvedwdlvqtlgegagevqlavnrvteeavavkivdmnikkeicinkmlnhenvvkfy
ghriqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpen
lllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscg
ivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsarit
ipdikkdrwynkplkkg