PDB entry 3p7g

View 3p7g on RCSB PDB site
Description: Structure of the human Langerin carbohydrate recognition domain in complex with mannose
Class: immune system
Keywords: C-type lectin, membrane protein, glycoprotein, Langerin, DC-SIGN, Carbohydrate binding protein, Calcium binding, sugar binding, Immune system, Langerhans cells, CD207
Deposited on 2010-10-12, released 2010-11-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-11-03, with a file datestamp of 2010-10-29.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.173
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K, Leucocyte cDNA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71 (Start-135)
      • expression tag (136-139)
    Domains in SCOPe 2.04: d3p7ga_
  • Chain 'B':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K, Leucocyte cDNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3p7gb_
  • Chain 'C':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K, Leucocyte cDNA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • expression tag (138)
    Domains in SCOPe 2.04: d3p7gc1
  • Chain 'D':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K, Leucocyte cDNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3p7gd_
  • Heterogens: CA, MAN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3p7gA (A:)
qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
igltkagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcd
ktflfickrpyvpsepsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >3p7gA (A:)
gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
agmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktflf
ickrpyvpsepsaws

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3p7gB (B:)
qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
igltkagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcd
ktflfickrpyvpsepsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >3p7gB (B:)
sqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigl
tkagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktf
lfickrpyvp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3p7gC (C:)
qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
igltkagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcd
ktflfickrpyvpsepsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >3p7gC (C:)
gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
agmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktflf
ickrpyvpsw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3p7gD (D:)
qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
igltkagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcd
ktflfickrpyvpsepsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >3p7gD (D:)
sqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigl
tkagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktf
lfickrpyvp