PDB entry 3p08

View 3p08 on RCSB PDB site
Description: Crystal structure of the human BTK kinase domain
Class: transferase
Keywords: b-cell, alpha/beta, kinase, phosphorylation, cytosol, TRANSFERASE
Deposited on 2010-09-27, released 2010-11-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-11-03, with a file datestamp of 2010-10-29.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.228
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: AGMX1, ATK, BPK, BTK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3p08a_
  • Chain 'B':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: AGMX1, ATK, BPK, BTK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3p08b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3p08A (A:)
gsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnl
sheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyl
eskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlmys
kfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimys
cwhekaderptfkillsnildvmdees

    Sequence, based on observed residues (ATOM records): (download) 
    >3p08A (A:)
sweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnls
heklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyle
skqflhrdlaarnclvndqgvvkvsdfglsrkfpvrwsppevlmyskfssksdiwafgvl
mweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhekaderptfki
llsnildvmdee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3p08B (B:)
gsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnl
sheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyl
eskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlmys
kfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimys
cwhekaderptfkillsnildvmdees

    Sequence, based on observed residues (ATOM records): (download) 
    >3p08B (B:)
weidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnlsh
eklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyles
kqflhrdlaarnclvndqgvvkvsdfglsryvlddeytfpvrwsppevlmyskfssksdi
wafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhekade
rptfkillsnildvmdee