PDB entry 3owl

View 3owl on RCSB PDB site
Description: Human CK2 catalytic domain in complex with a benzopyridoindole derivative inhibitor
Class: transferase/transferase inhibitor
Keywords: SERINE/THREONINE-PROTEIN KINASE, CK2, inhibitor, pyridocarbazol, ellipticine, Transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-09-20, released 2010-12-15
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-01-05, with a file datestamp of 2010-12-31.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.208
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CSNK2A1 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: csnk2a1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3owla_
  • Heterogens: 19E, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3owlA (A:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdq

    Sequence, based on observed residues (ATOM records): (download) 
    >3owlA (A:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdq