PDB entry 3osk

View 3osk on RCSB PDB site
Description: Crystal structure of human CTLA-4 apo homodimer
Class: immune system
Keywords: Beta sandwich, Homodimer, Immunoglobulin superfamily (beta sandwich) fold, Receptor, Signalling, B7-1(CD80), B7-2(CD86), Membrane, IMMUNE SYSTEM
Deposited on 2010-09-09, released 2010-12-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-02-05, with a file datestamp of 2014-01-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.203
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytotoxic t-lymphocyte protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CD152, CTLA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3oska_
  • Chain 'B':
    Compound: cytotoxic t-lymphocyte protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CD152, CTLA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3oskb_
  • Heterogens: NAG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3oskA (A:)
    kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
    tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
    pcpdsdlvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >3oskA (A:)
    mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
    lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpepc
    p
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3oskB (B:)
    kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
    tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
    pcpdsdlvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >3oskB (B:)
    mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
    lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpepc
    pds