PDB entry 3ori

View 3ori on RCSB PDB site
Description: Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 1)
Class: transferase
Keywords: Structural Genomics, TB Structural Genomics Consortium, TBSGC, Kinase, Signal transduction, TRANSFERASE
Deposited on 2010-09-07, released 2010-12-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-01-18, with a file datestamp of 2017-01-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine protein kinase
    Species: Mycobacterium tuberculosis [TaxId:419947]
    Gene: MRA_0016, pknB, PknB (Rv0014c)
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5TY84
      • engineered mutation (35)
    Domains in SCOPe 2.08: d3oria_
  • Chain 'B':
    Compound: Serine/threonine protein kinase
    Species: Mycobacterium tuberculosis [TaxId:419947]
    Gene: MRA_0016, pknB, PknB (Rv0014c)
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5TY84
      • engineered mutation (35)
    Domains in SCOPe 2.08: d3orib_
  • Chain 'C':
    Compound: Serine/threonine protein kinase
    Species: Mycobacterium tuberculosis [TaxId:419947]
    Gene: MRA_0016, pknB, PknB (Rv0014c)
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5TY84
      • engineered mutation (35)
    Domains in SCOPe 2.08: d3oric_
  • Chain 'D':
    Compound: Serine/threonine protein kinase
    Species: Mycobacterium tuberculosis [TaxId:419947]
    Gene: MRA_0016, pknB, PknB (Rv0014c)
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5TY84
      • engineered mutation (35)
    Domains in SCOPe 2.08: d3orid_
  • Heterogens: AGS, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3oriA (A:)
gshmttpshlsdryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfr
reaqnaaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraie
viadacqalnfshqngiihrdvkpanimisatnavkvmdfgiaraiadsgnsvtqtaavi
gtaqylspeqargdsvdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpipps
arheglsadldavvlkalaknpenryqtaaemradlvrvhngeppeapkvltdaertsll
ssaagnlsgpr

    Sequence, based on observed residues (ATOM records): (download) 
    >3oriA (A:)
ryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfrreaqnaaalnhp
aivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviadacqalnfs
hqngiihrdvkpanimisatnavkvmdfgiaraigtaqylspeqargdsvdarsdvyslg
cvlyevltgeppftgdspvsvayqhvredpippsarheglsadldavvlkalaknpenry
qtaaemradlvrvhngeppeapkvltd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3oriB (B:)
gshmttpshlsdryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfr
reaqnaaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraie
viadacqalnfshqngiihrdvkpanimisatnavkvmdfgiaraiadsgnsvtqtaavi
gtaqylspeqargdsvdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpipps
arheglsadldavvlkalaknpenryqtaaemradlvrvhngeppeapkvltdaertsll
ssaagnlsgpr

    Sequence, based on observed residues (ATOM records): (download) 
    >3oriB (B:)
ryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfrreaqnaaalnhp
aivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviadacqalnfs
hqngiihrdvkpanimisatnavkvmdfgiaraigtaqylspeqargdsvdarsdvyslg
cvlyevltgeppftgdspvsvayqhvredpippsarheglsadldavvlkalaknpenry
qtaaemradlvrvhngeppeapkvltd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3oriC (C:)
gshmttpshlsdryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfr
reaqnaaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraie
viadacqalnfshqngiihrdvkpanimisatnavkvmdfgiaraiadsgnsvtqtaavi
gtaqylspeqargdsvdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpipps
arheglsadldavvlkalaknpenryqtaaemradlvrvhngeppeapkvltdaertsll
ssaagnlsgpr

    Sequence, based on observed residues (ATOM records): (download) 
    >3oriC (C:)
ryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfrreaqnaaalnhp
aivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviadacqalnfs
hqngiihrdvkpanimisatnavkvmdfgiaraigtaqylspeqargdsvdarsdvyslg
cvlyevltgeppftgdspvsvayqhvredpippsarheglsadldavvlkalaknpenry
qtaaemradlvrvhngeppeapkvltd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3oriD (D:)
gshmttpshlsdryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfr
reaqnaaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraie
viadacqalnfshqngiihrdvkpanimisatnavkvmdfgiaraiadsgnsvtqtaavi
gtaqylspeqargdsvdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpipps
arheglsadldavvlkalaknpenryqtaaemradlvrvhngeppeapkvltdaertsll
ssaagnlsgpr

    Sequence, based on observed residues (ATOM records): (download) 
    >3oriD (D:)
ryelgeilgfggmsevhlardlrdhrdvavkvlradlardpsfylrfrreaqnaaalnhp
aivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviadacqalnfs
hqngiihrdvkpanimisatnavkvmdfgiaraigtaqylspeqargdsvdarsdvyslg
cvlyevltgeppftgdspvsvayqhvredpippsarheglsadldavvlkalaknpenry
qtaaemradlvrvhngeppeapkvltd