PDB entry 3oe1

View 3oe1 on RCSB PDB site
Description: Pyruvate decarboxylase variant Glu473Asp from Z. mobilis in complex with reaction intermediate 2-lactyl-ThDP
Class: lyase
Keywords: Lyase
Deposited on 2010-08-12, released 2010-09-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-01-12, with a file datestamp of 2011-01-07.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: 0.197
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Gene: pdc, ZMO1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06672
      • engineered (472)
    Domains in SCOPe 2.06: d3oe1a1, d3oe1a2, d3oe1a3
  • Chain 'B':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Gene: pdc, ZMO1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06672
      • engineered (472)
    Domains in SCOPe 2.06: d3oe1b1, d3oe1b2, d3oe1b3
  • Chain 'C':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Gene: pdc, ZMO1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06672
      • engineered (472)
    Domains in SCOPe 2.06: d3oe1c1, d3oe1c2, d3oe1c3
  • Chain 'D':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Gene: pdc, ZMO1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06672
      • engineered (472)
    Domains in SCOPe 2.06: d3oe1d1, d3oe1d2, d3oe1d3
  • Heterogens: MG, TDL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3oe1A (A:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >3oe1A (A:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3oe1B (B:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >3oe1B (B:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnaaapadpsaplv
naeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpaafgya
vgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgpynnikn
wdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigredcte
elvkwgkrvaaansrkpvnk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3oe1C (C:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >3oe1C (C:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3oe1D (D:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >3oe1D (D:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslndpsaplvnaeia
rqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpaafgyavgape
rrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytidvmihdgpynniknwdyag
lmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigredcteelvkw
gkrvaaansrkpvnk