PDB entry 3o2d

View 3o2d on RCSB PDB site
Description: Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
Class: immune system
Keywords: immunoglobulin fold, HIV-1 primary receptor, T cell coreceptor, monoclonal antibody, Membrane, IMMUNE SYSTEM
Deposited on 2010-07-22, released 2010-12-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-12-22, with a file datestamp of 2010-12-17.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: 0.194
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein cd4
    Species: Homo sapiens [TaxId:9606]
    Gene: CD4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3o2da1, d3o2da2
  • Chain 'H':
    Compound: ibalizumab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3O2D (0-End)
  • Chain 'L':
    Compound: ibalizumab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3O2D (0-End)
    Domains in SCOPe 2.06: d3o2dl1, d3o2dl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3o2dA (A:)
    kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
    lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
    ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlafq
    kahhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3o2dA (A:)
    kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
    lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
    ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvla
    

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >3o2dL (L:)
    divmtqspdslavslgervtmnckssqsllystnqknylawyqqkpgqspklliywastr
    esgvpdrfsgsgsgtdftltissvqaedvavyycqqyysyrtfgggtkleikrtvaapsv
    fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
    sstltlskadyekhkvyacevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records): (download)
    >3o2dL (L:)
    divmtqspdslavslgervtmnckssqsllystnqknylawyqqkpgqspklliywastr
    esgvpdrfsgsgsgtdftltissvqaedvavyycqqyysyrtfgggtkleikrtvaapsv
    fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
    sstltlskadyekhkvyacevthqglsspvtksfnr