PDB entry 3o23

View 3o23 on RCSB PDB site
Description: Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor
Class: transferase/transferase inhibitor
Keywords: Protein Kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-07-22, released 2011-05-04
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-05-04, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.238
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3o23a_
  • Heterogens: MQY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3o23A (A:)
saadvfvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasm
rerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemenn
pvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiy
etdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqv
lrfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyy
seenk

    Sequence, based on observed residues (ATOM records): (download) 
    >3o23A (A:)
ewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerieflne
asvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvlappsls
kmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkgg
kgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmeggl
ldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyse