PDB entry 3na1

View 3na1 on RCSB PDB site
Description: Crystal structure of human CYP11A1 in complex with 20-hydroxycholesterol
Class: Oxidoreductase, Electron transport
Keywords: cytochrome P450, 20-hydroxycholesterol, cholesterol side chain cleavage, Structural Genomics, Structural Genomics Consortium, SGC, Oxidoreductase, Electron transport
Deposited on 2010-05-31, released 2011-06-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cholesterol side-chain cleavage enzyme, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP11A, CYP11A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na1a_
  • Chain 'B':
    Compound: Cholesterol side-chain cleavage enzyme, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP11A, CYP11A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na1b_
  • Chain 'C':
    Compound: Adrenodoxin, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: adrenodoxin, ADX, FDX1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na1c_
  • Chain 'D':
    Compound: Adrenodoxin, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: adrenodoxin, ADX, FDX1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na1d_
  • Heterogens: HEM, HCD, FES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3na1A (A:)
strsprpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvy
vidpedvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevma
peatknflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqg
mleevvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiy
tqnfywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhly
emarnlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvn
dlvlrdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvr
qclgrriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpfnqeatq
qhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3na1A (A:)
sprpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvyvid
pedvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevmapea
tknflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqgmle
evvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiytqn
fywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhlyema
rnlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvndlv
lrdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvrqcl
grriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpfn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3na1B (B:)
strsprpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvy
vidpedvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevma
peatknflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqg
mleevvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiy
tqnfywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhly
emarnlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvn
dlvlrdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvr
qclgrriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpfnqeatq
qhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3na1B (B:)
prpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvyvidp
edvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevmapeat
knflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqgmlee
vvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiytqnf
ywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhlyemar
nlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvndlvl
rdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvrqclg
rriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpfn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3na1C (C:)
ssedkitvhfinrdgetlttkgkvgdslldvvvennldidgfgacegtlacstchlifed
hiyekldaitdeendmldlaygltdrsrlgcqicltksmdnmtvrvpetvadarqsidvg
kts

    Sequence, based on observed residues (ATOM records): (download) 
    >3na1C (C:)
gacegtlacstcdeendmldlalgcq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3na1D (D:)
ssedkitvhfinrdgetlttkgkvgdslldvvvennldidgfgacegtlacstchlifed
hiyekldaitdeendmldlaygltdrsrlgcqicltksmdnmtvrvpetvadarqsidvg
kts

    Sequence, based on observed residues (ATOM records): (download) 
    >3na1D (D:)
acegtlacstceendmldlalgcq