PDB entry 3mrp

View 3mrp on RCSB PDB site
Description: Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant
Class: immune system
Keywords: MHC class I, HLA, IMMUNE SYSTEM, IMMUNE RESPONSE, DECAPEPTIDE, TUMORAL PEPTIDE, MELAN-A, MART1
Deposited on 2010-04-29, released 2011-05-25
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-05-25, with a file datestamp of 2011-05-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.187
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA, HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01892 (0-End)
      • engineered mutation (244)
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, Beta-2 microglubulin, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.04: d3mrpb_
  • Chain 'P':
    Compound: 10-meric peptide from Melanoma antigen recognized by T-cells 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16655 (0-9)
      • see remark 999 (1)
      • engineered mutation (4)
      • engineered mutation (7)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3mrpB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'P':
    No sequence available.