PDB entry 3mrk
View 3mrk on RCSB PDB site
Description: Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide
Class: immune system
Keywords: MHC class I, HLA, IMMUNE SYSTEM, IMMUNE RESPONSE, NONAPEPTIDE, TUMORAL PEPTIDE, ALPHA-FETOPROTEIN
Deposited on
2010-04-29, released
2011-05-25
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-05-25, with a file datestamp of
2011-05-20.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.2
AEROSPACI score: 0.66
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA, HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Uniprot P01892 (0-End)
- engineered mutation (244)
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, Beta-2 microglubulin, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3mrkb1, d3mrkb2 - Chain 'P':
Compound: 9-meric peptide from Alpha-fetoprotein
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3mrkB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
Sequence, based on observed residues (ATOM records): (download)
>3mrkB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd
- Chain 'P':
No sequence available.