PDB entry 3mrd

View 3mrd on RCSB PDB site
Description: Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide V6G variant
Class: immune system
Keywords: MHC class I, HLA, IMMUNE SYSTEM, IMMUNE RESPONSE, NONAPEPTIDE, VIRAL PEPTIDE, CYTOMEGALOVIRUS, pp65 PROTEIN
Deposited on 2010-04-29, released 2011-05-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-01-28, with a file datestamp of 2015-01-23.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.196
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA, HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01892 (0-End)
      • engineered mutation (244)
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, Beta-2 microglubulin, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3mrdb_
  • Chain 'P':
    Compound: 9-meric peptide from Tegument protein pp65
    Species: Human Cytomegalovirus HCMV, synthetic [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6SW59 (0-8)
      • engineered mutation (5)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mrdB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >3mrdB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'P':
    No sequence available.