SCOPe 2.07: Structural Classification of Proteins

PDB entry 3mka

View 3mka on RCSB PDB site
Description: Crystal Structure of Mycobacterium Tuberculosis Proteasome with propetide and an T1A mutation at beta-subunit
Class: hydrolase
Keywords: Mycobacterium tuberculosis, Proteasome Endopeptidase Complex, Protein Subunits, Propeptide, Protein maturation, Proteasome Assembly, HYDROLASE
Deposited on 2010-04-14, released 2010-05-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-06-30, with a file datestamp of 2010-06-25.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: 0.217
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

Chain '1':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mka1_
Chain '2':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mka2_
Chain 'A':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkaa_
Chain 'B':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkab_
Chain 'C':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkac_
Chain 'D':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkad_
Chain 'E':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkae_
Chain 'F':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkaf_
Chain 'G':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkag_
Chain 'H':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkah_
Chain 'I':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkai_
Chain 'J':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkaj_
Chain 'K':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkak_
Chain 'L':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkal_
Chain 'M':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkam_
Chain 'N':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkan_
Chain 'O':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkao_
Chain 'P':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkap_
Chain 'Q':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkaq_
Chain 'R':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkar_
Chain 'S':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkas_
Chain 'T':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkat_
Chain 'U':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkau_
Chain 'V':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkav_
Chain 'W':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkaw_
Chain 'X':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkax_
Chain 'Y':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.07: d3mkay_
Chain 'Z':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245
  - engineered (57)
Domains in SCOPe 2.07: d3mkaz_
Heterogens: HOH

PDB Chain Sequences:

Chain '1':
Sequence, based on SEQRES records: (download)

>3mka1 (1:)
msfpyfispeqamrerselarkgiaraksvvalayaggvlfvaenpsrslqkiselydrv
gfaaagkfnefdnlrrggiqfadtrgyaydrrdvtgrqlanvyaqtlgtifteqakpyev
elcvaevahygetkrpelyritydgsiadephfvvmggttepianalkesyaenasltda
lriavaalragsadtsggdqptlgvaslevavldanrprrafrritgsalqallvdqesp
qsdgessg