PDB entry 3ma7

View 3ma7 on RCSB PDB site
Description: Crystal structure of Cardiolipin bound to mouse CD1D
Class: immune system
Keywords: GAMMA DELTA T CELLS, GLYCOLIPID PRESENTATION, MHC, CD1, CELL MEMBRANE, ENDOSOME, GLYCOPROTEIN, IMMUNE RESPONSE, IMMUNOGLOBULIN DOMAIN, INNATE IMMUNITY, LYSOSOME, MEMBRANE, TRANSMEMBRANE, MHC I, SECRETED, IMMUNE SYSTEM, Disulfide bond, Immunity
Deposited on 2010-03-23, released 2011-03-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD1d1
    Species: Mus musculus [TaxId:10090]
    Gene: Cd1.1, CD1d, Cd1d1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11609 (Start-278)
      • engineered mutation (200)
    Domains in SCOPe 2.07: d3ma7a1, d3ma7a2
  • Chain 'B':
    Compound: beta-2 microglobulin
    Species: Mus musculus [TaxId:10090]
    Gene: B2m, beta-2-microglobulin, mCG_11606, RP23-34E24.5-001
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ma7b_
  • Chain 'C':
    Compound: T-cell surface glycoprotein CD1d1
    Species: Mus musculus [TaxId:10090]
    Gene: Cd1.1, CD1d, Cd1d1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ma7c1, d3ma7c2
  • Chain 'D':
    Compound: beta-2 microglobulin
    Species: Mus musculus [TaxId:10090]
    Gene: B2m, beta-2-microglobulin, mCG_11606, RP23-34E24.5-001
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ma7d_
  • Heterogens: CD4, PLM, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3ma7A (A:)
    seaqqknytfrclqmssfanrswsrtdsvvwlgdlqthrwsndsatisftkpwsqgklsn
    qqweklqhmfqvyrvsftrdiqelvkmmspkedypieiqlsagcemypgnasesflhvaf
    qgkyvvrfwgtswqtvpgapswldlpikvlnadqgtsatvqmllndtcplfvrglleagk
    sdlekqekpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpn
    adetwylqatldveageeaglacrvkhsslggqdiilywhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ma7A (A:)
    nytfrclqmssfanrswsrtdsvvwlgdlqthrwsndsatisftkpwsqgklsnqqwekl
    qhmfqvyrvsftrdiqelvkmmspkedypieiqlsagcemypgnasesflhvafqgkyvv
    rfwgtswqtvpgapswldlpikvlnadqgtsatvqmllndtcplfvrglleagksdlekq
    ekpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpnadetwy
    lqatldveageeaglacrvkhsslggqdiilyw
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3ma7B (B:)
    iqktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskdw
    sfyilahteftptetdtyacrvkhasmaepktvywdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ma7B (B:)
    qktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskdws
    fyilahteftptetdtyacrvkhasmaepktvywdrdm
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3ma7C (C:)
    seaqqknytfrclqmssfanrswsrtdsvvwlgdlqthrwsndsatisftkpwsqgklsn
    qqweklqhmfqvyrvsftrdiqelvkmmspkedypieiqlsagcemypgnasesflhvaf
    qgkyvvrfwgtswqtvpgapswldlpikvlnadqgtsatvqmllndtcplfvrglleagk
    sdlekqekpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpn
    adetwylqatldveageeaglacrvkhsslggqdiilywhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ma7C (C:)
    nytfrclqmssfanrswsrtdsvvwlgdlqthrwsndsatisftkpwsqgklsnqqwekl
    qhmfqvyrvsftrdiqelvkmmdypieiqlsagcemypgsesflhvafqgkyvvrfwgts
    wqtvpgapswldlpikvlnadqgtsatvqmllndtcplfvrglleagksdlekqekpvaw
    lssvpssahrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpnadetwylqatldve
    ageeaglacrvkhsslggqdiilyw
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3ma7D (D:)
    iqktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskdw
    sfyilahteftptetdtyacrvkhasmaepktvywdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ma7D (D:)
    qktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskdws
    fyilahteftptetdtyacrvkhasmaepktvywdrdm