PDB entry 3m8p

View 3m8p on RCSB PDB site
Description: HIV-1 RT with NNRTI TMC-125
Class: transferase
Keywords: HIV, RT, REVERSE TRANSCRIPTASE RIBONUCLEASE H, TRANSFERASE RNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, Hydrolase, Transferase
Deposited on 2010-03-18, released 2010-05-19
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-07-18, with a file datestamp of 2012-07-13.
Experiment type: XRAY
Resolution: 2.67 Å
R-factor: 0.212
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: Human immunodeficiency virus type 1 [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3m8pa1, d3m8pa2
  • Chain 'B':
    Compound: p51 RT
    Species: Human immunodeficiency virus type 1 [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3m8pb_
  • Heterogens: 65B, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3m8pA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkvlf

    Sequence, based on observed residues (ATOM records): (download) 
    >3m8pA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faiktkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiyl
alqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgigg
neqvdklvsag

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3m8pB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >3m8pB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
stkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrky
taftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddl
yvgsdleigqhrtkieelrqhllrwglwmgyelhpdkwtvqpivlpekdswtvndiqklv
gklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydp
skdliaeiqkqgqgqwtyqiyqepfknlktgkyatndvkqlteavqkittesiviwgktp
kfklpiqketwetwwteywqatwipewefvntpplvklwyq