PDB entry 3lw8

View 3lw8 on RCSB PDB site
Description: Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex A)
Class: Signaling Protein/RHOA-BINDING PROTEIN
Keywords: IpgB2, RhoA, GTPase, GEF, GEF-GTPase-complex, WxxxE, TTSS effector protein, bacterial GEF, cytoskeleton dynamics, Signaling Protein-RHOA-BINDING PROTEIN complex
Deposited on 2010-02-23, released 2010-03-31
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.18
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RhoA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (5-184)
      • expression tag (0-4)
    Domains in SCOPe 2.03: d3lw8a_
  • Chain 'B':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RhoA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (5-184)
      • expression tag (0-4)
    Domains in SCOPe 2.03: d3lw8b_
  • Chain 'C':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RhoA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (5-184)
      • expression tag (0-4)
    Domains in SCOPe 2.03: d3lw8c_
  • Chain 'D':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RhoA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (5-184)
      • expression tag (4)
    Domains in SCOPe 2.03: d3lw8d_
  • Chain 'E':
    Compound: IpgB2
    Species: Shigella flexneri [TaxId:623]
    Gene: ipgB2
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: IpgB2
    Species: Shigella flexneri [TaxId:623]
    Gene: ipgB2
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: IpgB2
    Species: Shigella flexneri [TaxId:623]
    Gene: ipgB2
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: IpgB2
    Species: Shigella flexneri [TaxId:623]
    Gene: ipgB2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GDP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3lw8A (A:)
gplgsaairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvela
lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
aalqa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3lw8B (B:)
gplgsaairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvela
lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
aalqa

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3lw8C (C:)
gplgsaairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvela
lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
aalqa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3lw8D (D:)
gplgsaairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvela
lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
aalqa

    Sequence, based on observed residues (ATOM records): (download) 
    >3lw8D (D:)
saairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvelalwdt
agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
a

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.