PDB entry 3lw0

View 3lw0 on RCSB PDB site
Description: IGF-1RK in complex with ligand MSC1609119A-1
Class: transferase
Keywords: protein kinase, transferase
Deposited on 2010-02-23, released 2010-09-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3lw0a_
  • Chain 'B':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3lw0b_
  • Chain 'C':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3lw0c_
  • Chain 'D':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3lw0d_
  • Heterogens: CCX, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3lw0A (A:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpamannp
vlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiye
tdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvl
rfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyys
eenk

    Sequence, based on observed residues (ATOM records): (download) 
    >3lw0A (A:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpppslsk
miqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkgll
pvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkp
dncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3lw0B (B:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpamannp
vlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiye
tdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvl
rfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyys
eenk

    Sequence, based on observed residues (ATOM records): (download) 
    >3lw0B (B:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpppslsk
miqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkgll
pvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkp
dncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3lw0C (C:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpamannp
vlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiye
tdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvl
rfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyys
eenk

    Sequence, based on observed residues (ATOM records): (download) 
    >3lw0C (C:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpppslsk
miqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkgll
pvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkp
dncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3lw0D (D:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpamannp
vlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiye
tdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvl
rfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyys
eenk

    Sequence, based on observed residues (ATOM records): (download) 
    >3lw0D (D:)
aadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmr
erieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpppslsk
miqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkgll
pvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkp
dncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk