PDB entry 3lv3

View 3lv3 on RCSB PDB site
Description: Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent calcium channel alpha1 subunit (residues 513-521)
Class: immune system
Keywords: IMMUNE SYSTEM, MHC (MAJOR HISTOCOMPATIBILITY COMPLEX), HLA-B*2705, Disulfide bond, Glycoprotein, Immune response, Membrane, MHC I, Transmembrane, Amyloid, Amyloidosis, Disease mutation, Glycation, Immunoglobulin domain, Secreted, Calcium channel, Voltage-gated channel
Deposited on 2010-02-19, released 2010-11-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-10-31, with a file datestamp of 2012-10-26.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.178
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-27 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d3lv3b1, d3lv3b2
  • Chain 'C':
    Compound: 9-meric peptide from Voltage-dependent L-type calcium channel subunit alpha-1D
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3lv3B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.