PDB entry 3lpl

View 3lpl on RCSB PDB site
Description: E. coli pyruvate dehydrogenase complex E1 component E571A mutant
Class: oxidoreductase
Keywords: THDP, PYRUVATE DEHYDROGENASE, OXIDOREDUCTASE, Glycolysis, Metal-binding, Pyruvate, Thiamine pyrophosphate
Deposited on 2010-02-05, released 2010-03-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-02-15, with a file datestamp of 2012-02-10.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.197
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate dehydrogenase E1 component
    Species: Escherichia coli [TaxId:83334]
    Gene: aceE, B0114, ECs0118, Z0124
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AFG9 (Start-885)
      • engineered mutation (570)
    Domains in SCOPe 2.06: d3lpla1, d3lpla2, d3lpla3
  • Chain 'B':
    Compound: Pyruvate dehydrogenase E1 component
    Species: Escherichia coli [TaxId:83334]
    Gene: aceE, B0114, ECs0118, Z0124
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AFG9 (Start-885)
      • engineered mutation (570)
    Domains in SCOPe 2.06: d3lplb1, d3lplb2, d3lplb3
  • Heterogens: EPE, TDP, MG, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3lplA (A:)
serfpndvdpietrdwlqaiesvireegveraqylidqllaearkggvnvaagtgisnyi
ntipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssatiydvc
fnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgnglssyphp
klmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemdepeskg
aitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwgsrwde
llrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeqiwaln
rgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmdgvrhi
rdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqd
fgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiysp
ngqqytpqdreqvayykedekgqilqeginalgagcswlaaatsystnnlpmipfyiyys
mfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydp
ayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiykletie
gskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwnmlhpl
etprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhh
fevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

    Sequence, based on observed residues (ATOM records): (download) 
    >3lplA (A:)
isnyintipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssat
iydvcfnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgngls
syphpklmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemde
peskgaitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwg
srwdellrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeq
iwalnrgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaamdgvrhirdrfnvpv
sdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqdfgalleeq
skeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiyspedekgqil
qeginalgagcswlaaatsystnnlpmipfyiyysmfgfqrigdlcwaagdqqargflig
gtsgrttlngeglqhedghshiqsltipncisydpayayevavimhdglermygekqenv
yyyittlnenyhmpampegaeegirkgiykletiegskgkvqllgsgsilrhvreaaeil
akdygvgsdvysvtsftelardgqdcerwnmlhpletprvpyiaqvmndapavastdymk
lfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhhfevdasyvvvaalgelakrgeidkk
vvadaiakfnidadkvnprla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3lplB (B:)
serfpndvdpietrdwlqaiesvireegveraqylidqllaearkggvnvaagtgisnyi
ntipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssatiydvc
fnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgnglssyphp
klmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemdepeskg
aitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwgsrwde
llrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeqiwaln
rgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmdgvrhi
rdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqd
fgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiysp
ngqqytpqdreqvayykedekgqilqeginalgagcswlaaatsystnnlpmipfyiyys
mfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydp
ayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiykletie
gskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwnmlhpl
etprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhh
fevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

    Sequence, based on observed residues (ATOM records): (download) 
    >3lplB (B:)
isnyintipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssat
iydvcfnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgngls
syphpklmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemde
peskgaitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwg
srwdellrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeq
iwalnrgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaamdgvrhirdrfnvpv
sdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqdfgalleeq
skeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiyspedekgqil
qeginalgagcswlaaatsystnnlpmipfyiyysmfgfqrigdlcwaagdqqargflig
gtsgrttlngeglqhedghshiqsltipncisydpayayevavimhdglermygekqenv
yyyittlnenyhmpampegaeegirkgiykletiegskgkvqllgsgsilrhvreaaeil
akdygvgsdvysvtsftelardgqdcerwnmlhpletprvpyiaqvmndapavastdymk
lfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhhfevdasyvvvaalgelakrgeidkk
vvadaiakfnidadkvnprla