PDB entry 3lfq

View 3lfq on RCSB PDB site
Description: Crystal structure of CDK2 with SAR60, an aminoindazole type inhibitor
Class: Transferase
Keywords: protein kinase fold, Acetylation, ATP-binding, Cell cycle, Cell division, Kinase, Mitosis, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Transferase
Deposited on 2010-01-18, released 2010-03-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-04-07, with a file datestamp of 2010-04-02.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.187
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3lfqa_
  • Heterogens: A28, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3lfqA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3lfqA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirstaireisllkelnhpnivklldv
    ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
    pqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiwsl
    gcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfs
    kvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl