PDB entry 3lfn
View 3lfn on RCSB PDB site
Description: Crystal structure of CDK2 with SAR57, an aminoindazole type inhibitor
Class: Transferase
Keywords: protein kinase fold, Acetylation, ATP-binding, Cell cycle, Cell division, Kinase, Mitosis, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Transferase
Deposited on
2010-01-18, released
2010-03-02
The last revision prior to the SCOPe 2.02 freeze date was dated
2010-04-07, with a file datestamp of
2010-04-02.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: 0.19
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3lfna_ - Heterogens: A27, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3lfnA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>3lfnA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirtegvpstaireisllkelnhpniv
klldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvl
hrdlkpqnllintegaikladfglarahevvtlwyrapeillgckyystavdiwslgcif
aemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvp
pldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl