PDB entry 3lbz

View 3lbz on RCSB PDB site
Description: Crystal Structure of the BCL6 BTB domain complexed with the small molecule inhibitor 79-6
Class: transcription
Keywords: Transcription regulation, TRANSCRIPTION
Deposited on 2010-01-08, released 2010-04-28
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.215
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL5, BCL6, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3lbza_
  • Chain 'B':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL5, BCL6, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3lbzb_
  • Heterogens: Z88, Z89, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3lbzA (A:)
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dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3lbzA (A:)
sqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
rnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3lbzB (B:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3lbzB (B:)
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rnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as