PDB entry 3l9l
View 3l9l on RCSB PDB site
Description: Crystal structure of pka with compound 36
Class: transferase/transferase inhibitor
Keywords: PKB, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2010-01-05, released
2011-01-19
The last revision prior to the SCOPe 2.01 freeze date was dated
2011-11-16, with a file datestamp of
2011-11-11.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.219
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cAMP-dependent protein kinase catalytic subunit alpha
Species: Homo sapiens [TaxId:9606]
Gene: Prkaca, Pkaca
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3l9la_ - Chain 'B':
Compound: cAMP-dependent protein kinase catalytic subunit alpha
Species: Homo sapiens [TaxId:9606]
Gene: Prkaca, Pkaca
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3l9lb_ - Chain 'C':
Compound: cAMP-dependent protein kinase inhibitor alpha
Species: Homo sapiens [TaxId:9606]
Gene: PKIA, PRKACN1
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: cAMP-dependent protein kinase inhibitor alpha
Species: Homo sapiens [TaxId:9606]
Gene: PKIA, PRKACN1
Database cross-references and differences (RAF-indexed):
- Heterogens: L9L, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3l9lA (A:)
mgnaaaakkgseqesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvml
vkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymv
meyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgy
iqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppff
adqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfat
tdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
Sequence, based on observed residues (ATOM records): (download)
>3l9lA (A:)
eqesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvmlvkhketgnhya
mkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvpggemfs
hlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakr
vkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyeki
vsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkv
eapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3l9lB (B:)
mgnaaaakkgseqesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvml
vkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymv
meyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgy
iqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppff
adqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfat
tdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
Sequence, based on observed residues (ATOM records): (download)
>3l9lB (B:)
qesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvmlvkhketgnhyam
kildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvpggemfsh
lrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrv
kgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekiv
sgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkve
apfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.