PDB entry 3l3z

View 3l3z on RCSB PDB site
Description: Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid receptor coactivator 3
Class: protein binding
Keywords: androgen receptor, ligand binding domain, steroid receptor coactivator 3, 5-alpha-dihydrotestosterone (DHT), prostate cancer, PROTEIN BINDING
Deposited on 2009-12-18, released 2010-01-12
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-03-31, with a file datestamp of 2010-03-26.
Experiment type: XRAY
Resolution: N/A
R-factor: N/A
AEROSPACI score: -0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AR, DHTR, NR3C4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10275 (1-249)
      • expression tag (0)
    Domains in SCOPe 2.01: d3l3za_
  • Chain 'B':
    Compound: Nuclear receptor coactivator 3
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: DHT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3l3zA (A:)
sqpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnl
hvddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmr
hlsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrkn
ptscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkils
gkvkpiyfht

    Sequence, based on observed residues (ATOM records): (download) 
    >3l3zA (A:)
sqpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnl
hvddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmr
hlsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackknp
tscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfht

  • Chain 'B':
    No sequence available.