PDB entry 3l3m

View 3l3m on RCSB PDB site
Description: PARP complexed with A927929
Class: transferase
Keywords: Protein-Inhibitor Complex, Acetylation, ADP-ribosylation, DNA damage, DNA repair, DNA-binding, Glycosyltransferase, Metal-binding, NAD, Nucleus, Phosphoprotein, Transcription, Transcription regulation, Transferase
Deposited on 2009-12-17, released 2010-06-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-06-23, with a file datestamp of 2010-06-18.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.205
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly [ADP-ribose] polymerase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP1, ADPRT, PPOL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09874
      • engineered (100)
    Domains in SCOPe 2.06: d3l3ma1, d3l3ma2
  • Heterogens: A92, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3l3mA (A:)
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrgg
sddsskdpidvnyeklktdikvvdrdseeaeiirkyvknthatthnaydlevidifkier
egecqrykpfkqlhnrrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmv
sksanychtsqgdpiglillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsan
isldgvdvplgtgissgvndtsllyneyivydiaqvnlkyllklkfnfkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3l3mA (A:)
sklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavsq
gssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrggs
ddsskdpidvnyeklktdikvvdrdseeaeiirkyvknthatthnaydlevidifkiere
gecqrykpfkqlhnrrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmvs
ksanychtsqgdpiglillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsani
sldgvdvplgtgissgvndtsllyneyivydiaqvnlkyllklkfnfk