PDB entry 3l2c

View 3l2c on RCSB PDB site
Description: Crystal Structure of the DNA Binding Domain of FOXO4 Bound to DNA
Class: transcription/DNA
Keywords: forkhead, forkhead box, winged helix, TRANSCRIPTION-DNA COMPLEX
Deposited on 2009-12-15, released 2009-12-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-12-22, with a file datestamp of 2010-12-17.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: 0.195
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Forkhead box protein O4
    Species: Homo sapiens [TaxId:9606]
    Gene: AFX, AFX1, FOXO4, MLLT7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3l2ca_
  • Chain 'B':
    Compound: FOXO consensus binding sequence, plus strand
    Species: synthetic, synthetic
  • Chain 'C':
    Compound: FOXO consensus binding sequence, minus strand
    Species: synthetic, synthetic
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3l2cA (A:)
    gshmledpgavtgprkggsrrnawgnqsyaelisqaiesapekrltlaqiyewmvrtvpy
    fkdkgdsnssagwknsirhnlslhskfikvhneatgksswwmlnpeggks
    

    Sequence, based on observed residues (ATOM records): (download)
    >3l2cA (A:)
    rrnawgnqsyaelisqaiesapekrltlaqiyewmvrtvpyfkdkgdsnssagwknsirh
    nlslhskfikvhneatgksswwmln
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.