PDB entry 3kxz
View 3kxz on RCSB PDB site
Description: The complex crystal structure of LCK with a probe molecule w259
Class: Transferase
Keywords: LCK, Acetylation, ATP-binding, Cell membrane, Chromosomal rearrangement, Cytoplasm, Disease mutation, Host-virus interaction, Kinase, Lipoprotein, Membrane, Myristate, Nucleotide-binding, Palmitate, Phosphoprotein, Polymorphism, Proto-oncogene, Transferase, Tyrosine-protein kinase, Structural Genomics, Protein Structure Factory, PSF
Deposited on
2009-12-04, released
2010-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated
2010-06-23, with a file datestamp of
2010-06-18.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: 0.192
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Proto-oncogene tyrosine-protein kinase LCK
Species: Homo sapiens [TaxId:9606]
Gene: LCK
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3kxza_ - Heterogens: SO4, CA, 925, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3kxzA (A:)
gsqtqkpqkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmsp
daflaeanlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinkll
dmaaqiaegmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregakf
pikwtapeainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrp
dncpeelyqlmrlcwkerpedrptfdylrsvledfftategqyqpqp
Sequence, based on observed residues (ATOM records): (download)
>3kxzA (A:)
wevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaeanlmkqlqh
qrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiaegmafiee
rnyihrdlraanilvsdtlsckiadfglarliedneytaregakfpikwtapeainygtf
tiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmrlcw
kerpedrptfdylrsvledfftat