PDB entry 3kwg

View 3kwg on RCSB PDB site
Description: X-ray structure of NS1 effector domain W187A mutant
Class: viral protein
Keywords: influenza, NS1, effector domain, Host cytoplasm, Host nucleus, Host-virus interaction, Interferon antiviral system evasion, RNA-binding, Suppressor of RNA silencing, VIRAL PROTEIN
Deposited on 2009-12-01, released 2010-02-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-03-23, with a file datestamp of 2010-03-19.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: 0.189
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Non-structural protein 1
    Species: Influenza A virus [TaxId:381517]
    Gene: NS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03495 (Start-140)
      • engineered (122)
    Domains in SCOPe 2.08: d3kwga_
  • Chain 'B':
    Compound: Non-structural protein 1
    Species: Influenza A virus [TaxId:381517]
    Gene: NS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03495 (13-140)
      • expression tag (8)
      • expression tag (10-12)
      • engineered (122)
    Domains in SCOPe 2.08: d3kwgb1, d3kwgb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kwgA (A:)
mahhhhhhvddddkmtmastpasryitdmtieelsrdwfmlmpkqkvegplciridqaim
dknimlkanfsvifdrletlillrafteegaivgeisplpsfpghtiedvknaigvligg
leandntvrvsktlqrfawgs

    Sequence, based on observed residues (ATOM records): (download) 
    >3kwgA (A:)
tpasryitdmtieelsrdwfmlmpkqkvegplciridqaimdknimlkanfsvifdrlet
lillrafteegaivgeisplpsfpghtiedvknaigvliggleandntvrvsktlqrfaw
gs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kwgB (B:)
mahhhhhhvddddkmtmastpasryitdmtieelsrdwfmlmpkqkvegplciridqaim
dknimlkanfsvifdrletlillrafteegaivgeisplpsfpghtiedvknaigvligg
leandntvrvsktlqrfawgs

    Sequence, based on observed residues (ATOM records): (download) 
    >3kwgB (B:)
vddddkmtmastpasryitdmtieelsrdwfmlmpkqkvegplciridqaimdknimlka
nfsvifdrletlillrafteegaivgeisplpsfpghtiedvknaigvliggleandntv
rvsktlqrfawgs